AF/LE Purified Anti-Human CD80 Antibody[2D10]

LAB, CTLA-4 counter-receptor B, T-lymphocyte activation antigen CD, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7, CD80, CD28LGB7-1 antigen, T-lymphocyte activation antigen CD80, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1,  B7-1,  BB1, B lymphocyte activation antigen B7, B7-1 antigen, B7-1 antigen), CD28 antigen ligand 1, CD80 antigen, CD80 antigen (CD28 antigen ligand 1, CD80 molecule, Costimulatory factor CD80, costimulatory molecule variant IgV-CD80

2D10

Mouse IgG1, κ

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FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.

CD80

Mouse

Human

Monoclonal

>98%, Protein A/G purified

FCM

≥ 1 mg/mL

None (AF/LE)

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

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