AF/LE Purified Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

Cd47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47

MIAP410

Mouse IgG1, κ

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FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

CD47

Q08722, Q61735, P97829

Mouse

Human;Mouse;Rat

Monoclonal

FCM

≥ 1 mg/mL

None (AF/LE)

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

Ice bag