AF/LE Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7]

CD120b, TNF-R2, TNF-RII, TNFR-II, Tnfrsf1b, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, p75, p80 TNF-alpha receptor

TR75-54.7

Armenian Hamster IgG

咨询

CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

CD120b/TNFR2

Armenian Hamster

Mouse

Monoclonal

FCM;Block

≥ 1 mg/mL

None (AF/LE)

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

Ice bag