AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]

C-X-C chemokine receptor type 3, CD183/CXCR3, CXC-R3, CXCR-3, Cxcr3, IP-10 receptor, Interferon-inducible protein 10 receptor

CXCR3-173

Armenian Hamster IgG

咨询

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

CD183/CXCR3

Armenian Hamster

Mouse

Monoclonal

FCM;Block

≥ 1 mg/mL

None (AF/LE)

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

Ice bag