AF/LE Purified Anti-Mouse CD86 Antibody[GL-1]

Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86

GL-1

Rat IgG2a, κ

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FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

CD86

Rat

Mouse

Monoclonal

FCM

≥ 1 mg/mL

None (AF/LE)

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

Ice bag