AFP Polyclonal Antibody

Verified Samples in IHC: Human liver cancer

IHC 1:300-1:600

Polyclonal

IgG

Recombinant Human AEP protein expressed by E.coli

AFP

AFP, Alpha-fetoglobulin, Alpha-fetoprotein, HPAFP

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cancer, Cardiovascular, Developmental Biology

Unconjugated

Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin,AFP,vitamin D (Gc) protein,and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moiety. AFP is one of the several embryo-specific proteins and is a dominant serum protein as early in human embryonic life as one month,when albumin and transferrin are present in relatively small amounts. It is first synthesized in the human by the yolk sac and liver(1-2 months) and subsequently predominantly in the liver. A small amount of AFP is produced by the GI tract of the human conceptus. It has been proved that AFP may reappear in the serum in elevated amounts in adult life in association with normal restorative processes and with malignant growth. Alpha-fetoprotein (AFP) is a specific marker for hepatocellular carcinoma (HCC),teratoblastomas,and neural tube defect (NTD).