AFP Polyclonal Antibody

Verified Samples in WB: Hep G2, Mouse placenta, Rat placenta, Mouse Fetal liver, Rat Fetal liver, Mouse liver, Mouse kidney, Rat liver, Rat kidney
Verified Samples in IHC: Mouse liver, Human liver cancer, Human ovarian cancer, MCF-7, MCF-7, Human liver cancer

WB 1:500-1:1000, IHC 1:200-1:500, IF 1:100-1:200

Polyclonal

IgG

Recombinant Mouse Afp protein expressed by E.coli

AFP

AFPD,  Alpha fetoglobulin,  Alpha fetoprotein precursor,  Alpha-1-fetoprotein,  FETA,  HPAFP,  Hereditary persistence of alpha fetoprotein, Afp

67 kDa

73 kDa

Secreted

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cancer, Cardiovascular, Developmental Biology

Unconjugated

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.