APC Anti-Human CD326/EpCAM Antibody[9C4]

  • 货号:GFH1163E
APC Anti-Human CD326/EpCAM Antibody[9C4]
  • APC Anti-Human CD326/EpCAM Antibody[9C4]

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Size:
100 Tests 20 Tests 100 Tests × 2
Alternate Names
TROP1, Ep-CAM, EpCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1
Cellular Localization
Membrane
Clone No
Isotype
Mouse IgG2b, κ
Leadtime
咨询
Background
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.
Abbre
CD326
Swissprot
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype Control
APC Mouse IgG2b, κ Isotype Control[MPC-11]
Applications
FCM
Form
Liquid
Concentration
5 μL/Test
Conjugation
APC
Conjugation Information
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date
12个月
Shipping
冰袋
Gene ID
Human colon carcinoma cell line HT29 are stained with APC Anti-Human CD326 Antibody (filled gray histogram). Unstained Human colon carcinoma cell line HT29 (empty black histogram) are used as control.
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