APC Anti-Human CD8a Antibody[OKT-8]

  • 货号:GFH1110E
APC Anti-Human CD8a Antibody[OKT-8]
  • APC Anti-Human CD8a Antibody[OKT-8]

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Size:
100 Tests 20 Tests 100 Tests × 2
Alternate Names
CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Cellular Localization
Membrane
Clone No
Isotype
Mouse IgG2a, κ
Leadtime
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Background
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Abbre
CD8
Swissprot
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype Control
APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Applications
FCM
Form
Liquid
Concentration
5 μL/Test
Conjugation
APC
Conjugation Information
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date
12个月
Shipping
冰袋
Gene ID
Staining of normal human peripheral blood cells with APC Anti-Human CD8a Antibody[OKT-8] (filled gray histogram) or APC Mouse IgG2a, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.
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