APC Anti-Mouse CD119 Antibody[GR-20]

货号：GFH1115E

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100 Tests 50 Tests 100 Tests × 2

Alternate Names	CD119, IFN-gamma-R-alpha, IFN-gamma-R1, Ifngr1, Interferon gamma receptor 1
Cellular Localization	Membrane
Clone No	GR-20
Isotype	Rat IgG2a, κ
Leadtime	咨询
Background	CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.
Abbre	CD119
Swissprot	P15261
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	APC Rat IgG2a, κ Isotype Control[2A3]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	APC
Conjugation Information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	15979

C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD119 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

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