APC Anti-Mouse CD122/IL-2RB Antibody[5H4]
- 货号：GFH1029E
![APC Anti-Mouse CD122/IL-2RB Antibody[5H4]](http://files.elabscience.cn/assets/images/loading.png)
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| Alternate Names | IL-2R subunit beta, CD122, High affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2RB, Il2rb, Interleukin-2 receptor subunit beta, p70-75 |
| Cellular Localization |
Membrane
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| Clone No | |
| Isotype | Rat IgG2a, κ |
| Leadtime |
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| Background |
CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
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| Abbre | CD122 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control |
APC Rat IgG2a, κ Isotype Control[2A3] |
| Applications |
FCM
|
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
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