APC Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1]

货号：GFH1112E

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100 Tests 50 Tests 100 Tests × 2

Alternate Names	B220
Cellular Localization	Membrane
Clone No	RA3.3A 1/6.1
Isotype	Rat IgM, κ
Leadtime	咨询
Background	CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Fas<sup>lpr</sup> and MRL-Fas<sup>gld</sup> mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.
Abbre	CD45R
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	APC Rat IgM, κ Isotype Control[RTK2118]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	APC
Conjugation Information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	19264,5788

C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD45R/B220 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

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