APC Anti-Mouse CD8a Antibody[2.43]

货号：GFH9996E

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100 Tests 50 Tests 100 Tests × 2

Alternate Names	CD19 Molecule, CD19 Antigen, Differentiation Antigen CD19, B-Lymphocytes Surface Antigen B4, T-cell Surface Antigen Leu-12, CVID3, B4, B-lymphocyte Antigen CD19
Cellular Localization	Membrane
Clone No	2.43
Isotype	Rat IgG2b, κ
Leadtime	咨询
Background	CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Abbre	CD8a
Swissprot	P15391
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	APC Rat IgG2b, κ Isotype Control[LTF-2]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	APC
Conjugation Information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	12525

Staining of C57BL/6 murine splenocytes cells with PE Anti-Mouse CD3 Antibody and APC Anti-Mouse CD8a Antibody[2.43] (left) or APC Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.

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