APC Anti-Mouse F4/80 Antibody[CI:A3-1]

货号：GFH0995E

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Alternate Names	Gpf480, Adgre1, Adhesion G protein-coupled receptor E1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, Emr1
Cellular Localization	Membrane
Clone No	CI:A3-1
Isotype	Rat IgG2b, κ
Leadtime	咨询
Background	F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.
Abbre	F4/80
Swissprot	Q61549
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	APC Rat IgG2b, κ Isotype Control[LTF-2]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	APC
Conjugation Information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	13733

Staining of C57BL/6 murine abdominal macrophages elicited by Thioglycolate are stained with APC Anti-Mouse F4/80 Antibody[CI:A3-1] (filled gray histogram) or APC Rat IgG2b, κ Isotype Control (empty black histogram). Cells in the macrophages gate were used for analysis.

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