Biotin Anti-Mouse CD119 Antibody[GR-20]

CD119, IFN-gamma-R-alpha, IFN-gamma-R1, Ifngr1, Interferon gamma receptor 1

Membrane

GR-20

Rat IgG2a, κ

咨询

CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

CD119

Rat

Mouse

Monoclonal

Biotin Rat IgG2a, κ Isotype Control[2A3]

FCM

Liquid

0.5 mg/mL

Biotin

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

This product can be stored at 2-8°C for 12 months. Do not freeze.

12个月

冰袋