Biotin Anti-Mouse CD51 Antibody[RMV-7]

ITGAV, Integrin alpha-V, Integrin αV chain, Vitronectin Receptor, αV integrin

Membrane

RMV-7

Rat IgG1, κ

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CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

CD51

Rat

Mouse

Monoclonal

Biotin Rat IgG1, κ Isotype Control[HRPN]

FCM

Liquid

0.5 mg/mL

Biotin

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

This product can be stored at 2-8°C for 12 months. Do not freeze.

12个月

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