CCL2 Polyclonal Antibody

Verified Samples in IHC: Human liver, Mouse kidney, Human breast

IHC 1:100-1:300

Polyclonal

IgG

Recombinant Human C-C motif chemokine 2 protein

CCL2

C-C motif chemokine 2, CCL2, Chemokine (C C motif) ligand 2, GDCF 2, GDCF-2, GDCF2, HC11, HSMCR30, JE, MCAF, MCP 1, MCP-1, MCP1, MGC9434, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretor

Secreted

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cancer, Cardiovascular, Metabolism, Immunology

Unconjugated

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.