CD74 Polyclonal Antibody

Verified Samples in IHC: Human tonsil, Human lung

IHC 1:200-1:400

Polyclonal

IgG

Recombinant Mouse Cd74 protein expressed by E.coli

CD74

CD 74, CD74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, CD74 molecule, CLIP, DHLAG, Gamma chain of class II antigens, class II antigen-associated), class II invariant chain, major histocompatibility complex

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cancer, Immunology

Unconjugated

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.