CK19 Polyclonal Antibody

Verified Samples in IHC: Human lung cancer, Human colon

IHC 1:100-1:300

Polyclonal

IgG

Recombinant Rat Krt19 protein expressed by E.coli

CK19

40 kd,  CK 19,  CK-19,  CK19,  Cytokeratin 19,  Cytokeratin-19,  K19,  K1C19,  K1CS,  Kera,  Keratin,  Keratin 19,  Keratin type I 40 kD,  Keratin type I 40kD,  Keratin type I cytoskeletal 19,  type I cytoskeletal 19, 40 kDa keratin intermediate filament, type I

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cancer, Signal Transduction

Unconjugated

The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19,one of type I keratins,is specifically expressed in the periderm,the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity,KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes,peripheral blood,and bone marrow of breast cancer patients. This antibody,generated against full length KRT19 protein,also recognizes KRT17,another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.