CK-7 Polyclonal Antibody

Verified Samples in WB: Mouse lung, Human A431, Human Hela, Human A549
Verified Samples in IHC: Mouse colon, Mouse kidney

WB 1:500-1:2000, IHC 1:250-1:500

Polyclonal

IgG

Recombinant Mouse Krt7 protein expressed by E.coli

CK-7

Cytokeratin 7,  D15Wsu77e,  K2C7,  K7,  Keratin 7,  Keratin type II cytoskeletal 7,  Krt2-7,  MGC11625,  Sarcolectin,  Type II mesothelial keratin K7, CK 7

51 kDa

51 kDa

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cancer, Signal Transduction

Unconjugated

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells,which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins,including K9–K23,and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins,including K1–K8,and the hair keratins,Hb1–Hb6. KRT7,also named as cytokeratin 7,is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels,and their neoplasms. KRT7 is marker of epithelial tissues,but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.