Elab Fluor® 488 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
- 货号：GFH1132L
![Elab Fluor® 488 Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]](http://files.elabscience.cn/assets/images/loading.png)
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| Alternate Names | B7-H1, PD-L1, Programmed cell death ligand 1, B7 homolog 1, B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1 |
| Cellular Localization |
Membrane
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| Clone No | |
| Isotype | Rat IgG2b, κ |
| Leadtime |
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| Background |
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
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| Abbre | CD274 |
| Swissprot | |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Isotype Control |
Elab Fluor® 488 Rat IgG2b, κ Isotype Control[LTF-2] |
| Applications |
FCM
|
| Form | Liquid |
| Concentration | 5 μL/Test |
| Conjugation | Elab Fluor®488 |
| Conjugation Information | Elab Fluor® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 12个月 |
| Shipping |
冰袋 |
| Gene ID |
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