Elab Fluor®700 Anti-Human CD279/PD-1 Antibody[EH12.2H7]

货号：GFH1229M1

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100 Tests 20 Tests 100 Tests × 2

Alternate Names	PD1, PDCD1, Protein PD-1, hPD-1
Cellular Localization	Membrane
Clone No	EH12.2H7
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Abbre	CD279
Swissprot	Q15116
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	Elab Fluor®700 Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	5133

Staining of the MOLT-4 cells with Elab Fluor^®700 Anti-Human CD279/PD-1 Antibody[EH12.2H7](filled gray histogram) or Elab Fluor^®700 Mouse IgG1, κ Isotype Control(empty black histogram).Total viable cells were used for analysis.

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