Elab Fluor®700 Anti-Human CD40 Antibody[3A8]

货号：GFH1037M1

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100 Tests 20 Tests 100 Tests × 2

Alternate Names	B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5
Cellular Localization	Membrane
Clone No	3A8
Isotype	Mouse IgG2a, κ
Leadtime	咨询
Background	CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
Abbre	CD40
Swissprot	P25942
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	Elab Fluor®700 Mouse IgG2a, κ Isotype Control[C1.18.4]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	958

Staining of normal human peripheral blood cells with Elab Fluor^® 700 Anti-Human CD40 Antibody[3A8] (filled gray histogram) or Elab Fluor^® 700 Mouse IgG2a, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.

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