Elab Fluor®700 Anti-Human CD8a Antibody[OKT-8]

货号：GFH1110M1

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100 Tests 20 Tests 100 Tests × 2

Alternate Names	CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Cellular Localization	Membrane
Clone No	OKT-8
Isotype	Mouse IgG2a, κ
Leadtime	咨询
Background	CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Abbre	CD8
Swissprot	P01732
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	Elab Fluor®700 Mouse IgG2a, κ Isotype Control[C1.18.4]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	925

Staining of normal human peripheral blood cells with Elab Fluor^® 700 Anti-Human CD8a Antibody[OKT-8] (filled gray histogram) or Elab Fluor^® 700 Mouse IgG2a, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.

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