Elab Fluor®700 Anti-Human IL-21 Antibody[3A3-N2]

货号：GFH1202M1

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100 Tests 20 Tests 100 Tests × 2

Alternate Names	IL-21, Interleukin-21, Za11
Cellular Localization	Secreted
Clone No	3A3-N2
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
Abbre	IL-21
Swissprot	Q9HBE4
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	Elab Fluor®700 Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	59067

Intracellular staining of the 293T cells transfected with pcDNA3.1 plasmid encoding Human IL-21 gene with Elab Fluor^®700 Anti-Human IL-21 Antibody[3A3-N2](filled gray histogram) or Elab Fluor^®700 Mouse IgG1, κ Isotype Control(empty black histogram). Total viable cells were used for analysis.

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