Elab Fluor®700 Anti-Mouse CD105 Antibody[MJ7/18]

货号：GFH1233M1

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Alternate Names	END, Endoglin, Eng
Cellular Localization	Membrane
Clone No	MJ7/18
Isotype	Rat IgG2a, κ
Leadtime	咨询
Background	CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
Abbre	CD105
Swissprot	Q63961
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	Elab Fluor®700 Rat IgG2a, κ Isotype Control[2A3]
Applications	FCM
Form	Liquid
Conjugation	Elab Fluor®700
Conjugation Information	Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	13805

Staining of the Mouse endothelial cells (bEnd.3) with Elab Fluor^®700 Anti-Mouse CD105 Antibody[MJ7/18](filled gray histogram) or Elab Elab Fluor^®700 Rat IgG2a, κ Isotype Control(empty black histogram). Total viable cells were used for analysis.

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武汉市高新大道858号光谷生物医药产业园二期B18栋