Elab Fluor®700 Anti-Mouse CD172a/SIRPα Antibody[P84]

BIT, CD172 antigen-like family member A, P84, PTPNS1, SHPS-1, SIRPα

Membrane

P84

Rat IgG1, κ

咨询

CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.

CD172a

Rat

Mouse

Monoclonal

Elab Fluor®700 Rat IgG1, κ Isotype Control[HRPN]

FCM

Liquid

Elab Fluor®700

Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

12个月

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