Elab Fluor®700 Anti-Mouse CD200/OX2 Antibody[OX-90]

MRC, OX-2, OX-2 membrane glycoprotein

Membrane

OX-90.3.9.8

Rat IgG2a, κ

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CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons); but not on NK cells, granulocytes, monocytes, or macrophages.  CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues.  CD200 is the ligand for CD200 receptor (CD200R).  The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity.  Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.

CD200

Rat

Mouse

Monoclonal

Elab Fluor®700 Rat IgG2a, κ Isotype Control[2A3]

FCM

Liquid

Elab Fluor®700

Elab Fluor^® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

12个月

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