Elab Fluor®Violet 540 Anti-Human CD45 Antibody[HI30]

  • 货号:GFH1137T3
Elab Fluor®Violet 540 Anti-Human CD45 Antibody[HI30]
  • Elab Fluor®Violet 540 Anti-Human CD45 Antibody[HI30]

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Size:
100 Tests 20 Tests 100 Tests × 2
Alternate Names
CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200
Cellular Localization
Membrane
Clone No
Isotype
Mouse IgG1, κ
Leadtime
咨询
Background
CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Abbre
CD45
Swissprot
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype Control
Elab Fluor®Violet 540 Mouse IgG1, κ Isotype Control[MOPC-21]
Applications
FCM
Form
Liquid
Conjugation
Elab Fluor®Violet 540
Conjugation Information
Elab Fluor®Violet 540 is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 548 nm (e.g., a 572/28 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date
12个月
Shipping
冰袋
Gene ID
Staining of normal human peripheral blood cells with Elab Fluor®Violet 540 Anti-Human CD45 Antibody[HI30](filled gray histogram) or Elab Fluor®Violet 540 Mouse IgG1, κ Isotype Control(empty black histogram). Cells in the lymphocytes gate were used for analysis.
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