FGG Polyclonal Antibody

Verified Samples in WB: Rat liver, Mouse liver
Verified Samples in IHC: Human liver, Human placenta

WB 1:1000-1:3000, IHC 1:100-1:300

Polyclonal

IgG

Recombinant Mouse Fibrinogen gamma chain protein

FGG

Fibrinogen gamma chain,  Fibrinogen gamma polypeptide, FGG

49 kDa

49 kDa

Secreted

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cardiovascular

Unconjugated

The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.