FITC Anti-Human CD279/PD-1 Antibody[EH12.2H7]

货号：GFH1229C

Price: ¥2088.00 ¥792.00 ¥3168.00

Size:

100 Tests 20 Tests 100 Tests × 2

Alternate Names	PD1, PDCD1, Protein PD-1, hPD-1
Cellular Localization	Membrane
Clone No	EH12.2H7
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Abbre	CD279
Swissprot	Q15116
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	5133

MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with FITC Anti-Human CD279/PD-1 Antibody (filled gray histogram) or FITC Mouse IgG1, κ Isotype Control (empty black histogram).

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