FITC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]

B7H1PD-L1PDCD1L1PDCD1LG1PDL1, B7 homolog 1, B7-H, B7-H1, Programmed cell death ligand 1

Membrane

10F.9G2

Rat IgG2b, κ

咨询

CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.

CD274

Rat

Mouse

Monoclonal

FITC Rat IgG2b, κ Isotype Control[LTF-2]

FCM

Liquid

0.5 mg/mL

FITC

FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

12个月

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