FITC Anti-Mouse FcεRIα Antibody[MAR-1]

  • 货号:GFH1188UC
FITC Anti-Mouse FcεRIα Antibody[MAR-1]
  • FITC Anti-Mouse FcεRIα Antibody[MAR-1]

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Size:
100 μg 25 μg
Alternate Names
Fc-epsilon RI-alpha, FcERI, Fcer1a, High affinity immunoglobulin epsilon receptor subunit alpha
Cellular Localization
Membrane
Clone No
Isotype
Armenian Hamster IgG
Leadtime
咨询
Background
FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.
Abbre
FcεRIα
Swissprot
Host
Armenian Hamster
Reactivity
Mouse
Clonality
Monoclonal
Isotype Control
FITC Armenian Hamster IgG Isotype Control[PIP]
Applications
FCM
Form
Liquid
Concentration
0.5 mg/mL
Conjugation
FITC
Conjugation Information
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date
12个月
Shipping
冰袋
Gene ID
C57BL/6 murine bone marrow cells are stained with APC Anti-Mouse CD49b Antibody and FITC Anti-Mouse FcεRIα Antibody (Left). Bone marrow cells stained with APC Anti-Mouse CD49b Antibody and FITC Armenian Hamster IgG Isotype Control (Right) are used as control.
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