FITC Anti-Mouse/Rat Foxp3 Antibody[FJK-16s]

货号：GFH1351C

Price: ¥3120.00 ¥1680.00 ¥4680.00

Size:

100 Tests 50 Tests 100 Tests × 2

Alternate Names	IPEXJM2ScurfinZinc finger protein JM2, Forkhead box protein P3
Cellular Localization	Nucleus;Cytoplasm
Clone No	FJK-16s
Isotype	Rat IgG2a, κ
Leadtime	咨询
Background	FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4<sup>+</sup>/CD25<sup>-</sup> cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity.
Abbre	Foxp3
Swissprot	Q99JB6
Host	Rat
Reactivity	Mouse;Rat
Clonality	Monoclonal
Isotype Control	FITC Rat IgG2a, κ Isotype Control[2A3]
Applications	ICFCM
Form	Liquid
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	20371

C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Anti-Mouse/Rat FOXP3 Antibody[FJK-16s] (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).

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