Galectin 3 Polyclonal Antibody

Verified Samples in WB: Human MCF-7, Mouse NIH/3T3, Mouse Raw264.7
Verified Samples in IHC: Human colon cancer, Human stomach cancer

WB 1:500-1:2000, IHC 1:150-1:300

Polyclonal

IgG

Recombinant Human LGALS3 protein expressed by E.coli

Galectin

35 kDa lectin, CBP 35, CBP35, Carbohydrate binding protein 35, Carbohydrate-binding protein 35, GAL3, GALBP, GALIG, GBP, Gal-3, Galactose-specific lectin 3, Galactoside-binding protein, Galectin 3 internal gene, Galectin-3, Galectin3, IgE binding protein, IgE-bi, included

26 kDa

26 kDa

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells, Cancer

Unconjugated

Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space. Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis.