IL6R Polyclonal Antibody

Verified Samples in WB: Rat spleen, Rat liver, Jurkat, Mouse spleen, Hela, Mouse liver
Verified Samples in IHC: Mouse spleen, Rat spleen

WB 1:1000-1:2000, IHC 1:100-1:300

Polyclonal

IgG

Recombinant Human Interleukin-6 receptor subunit alpha protein

IL6R

Membrane glycoprotein, CD126, gp80, IL6Q, IL-6R, IL-6R 1, IL-6R subunit alpha, IL-6R-1, IL6RA, IL-6RA, IL-6R-Alpha, IL6RQ, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, IL6R, IL-6R&, alpha, alpha, CD 126, CD126 antigen, IL 6R, IL 6R 1, IL 6R alpha, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, IL-6R 1 Membrane glycoprotein 80 (gp80), Interleukin 6 receptor, MGC30256

40,51 kDa

80 kDa

Cell membrane, Membrane, Secreted.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cancer, Immunology, Stem Cells

Unconjugated

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.