JAK1 Polyclonal Antibody
- 货号：GA006070L
Price:
Size:
100 μL
25 μL
| Verified Samples |
Verified Samples in IHC: Human breast cancer |
| Dilution | IHC 1:100-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human JAK1 protein expressed by E.coli |
| Abbre | JAK1 |
| Synonyms | JTK, JAK1, JAK1A, Janus kinase, Tyrosine-protein kinase JAK, JAK, JAK1, JAK1A, JAK1B, JTK3, JAK 1, JAK 1A, JAK 1B, JAK-1, Janus kinase 1, Janus kinase 1 (a protein tyrosine kinase), Tyrosine protein kinase JAK 1, Tyrosine protein kinase JAK1, Tyrosine-protein kinase JAK1 |
| Swissprot | |
| Cellular Localization | Endomembrane system |
| Tissue Specificity | Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue. |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cell Biology, Signal Transduction, Epigenetics and Nuclear Signaling, Cancer |
| Conjugation | Unconjugated |
| Background | This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. |
Immunohistochemistry of paraffin-embedded Human breast cancer using JAK1 Polyclonal Antibody at dilution of 1:200.
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