L1CAM Polyclonal Antibody

Verified Samples in WB: Mouse brain, Rat brain
Verified Samples in IHC: Mouse brain, Rat brain

WB 1:500-1:1000

Polyclonal

IgG

Recombinant Mouse L1cam protein expressed by E.coli

L1CAM

CAML1,  CD171,  CD171 antigen,  HSAS,  HSAS1,  Hyd,  L1,  L1 cell adhesion molecule,  L1cam,  MASA,  MIC5,  NCAML1,  NILE,  Nerve-growth factor-inducible large external glycoprotein,  Neural cell adhesion molecule L1,  OTTHU, Antigen identified by monoclonal antibody R1

140 kDa

140, 220kDa

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Signal Transduction, Neuroscience

Unconjugated

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.