MAP2K6 Polyclonal Antibody

Verified Samples in IHC: Mouse brain, Rat brain

IHC 1:50-1:100

Polyclonal

IgG

Recombinant Mouse Dual specificity mitogen-activated protein kinase kinase 6 protein

MAP2K6

MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3

Cytoskeleton, Cytosol, Nucleus, nucleoplasm, nucleus, Other locations: cytoplasm.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Antigen Affinity Purification

Cell Biology, Immunology, Signal transduction

Unconjugated

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.