PE Anti-Human CD86 Antibody[BU63]

货号：GFH1012D

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100 Tests 20 Tests 100 Tests × 2

Alternate Names	Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86
Cellular Localization	Membrane
Clone No	BU63
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Abbre	CD86
Swissprot	P42081
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	PE Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	942

Staining of normal human peripheral blood cells with Anti-Human CD14 APC and Anti-Human CD86 PE (left) or Mouse IgG1, κ Isotype Control PE (right). Cells in the monocyte gate were used for analysis.

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