PE Anti-Human CD8 Antibody[UCHT-4]

货号：GFH00427D

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100 Tests 20 Tests 100 Tests × 2

Alternate Names	T8, Leu2
Cellular Localization	Membrane
Clone No	UCHT-4
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck
Abbre	CD8
Swissprot	P01732
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	PE Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	925

Staining of normal human peripheral blood cells with PE Anti-Human CD8 Antibody[UCHT-4] (filled gray histogram) or PE Mouse IgG1, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.

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