PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]

货号：GFH1132D

Price: 询价询价询价

Size:

100 Tests 50 Tests 100 Tests × 2

Alternate Names	B7H1PD-L1PDCD1L1PDCD1LG1PDL1, B7 homolog 1, B7-H, B7-H1, Programmed cell death ligand 1
Cellular Localization	Membrane
Clone No	10F.9G2
Isotype	Rat IgG2b, κ
Leadtime	咨询
Background	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Abbre	CD274
Swissprot	Q9EP73
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	PE Rat IgG2b, κ Isotype Control[LTF-2]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	60533

Staining of C57BL/6 murine splenocytes with APC Anti-Mouse CD3 Antibody[17A2] and PE Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] (left) or PE Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.

联系我们

027-65384716

svipmaster@elabscience.cn

武汉市高新大道858号光谷生物医药产业园二期B18栋