PE Anti-Mouse CD40 Antibody[FGK4.5/FGK45]

货号：GFH1028D

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100 Tests 50 Tests 100 Tests × 2

Alternate Names	B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, Cd40, Tnfrsf5, Tumor necrosis factor receptor superfamily member 5
Cellular Localization	Membrane
Clone No	FGK4.5/FGK45
Isotype	Rat IgG2a, κ
Leadtime	咨询
Background	CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Abbre	CD40
Swissprot	P27512
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	PE Rat IgG2a, κ Isotype Control[2A3]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	21939

Staining of C57BL/6 murine splenocytes with APC Anti-Mouse CD19 Antibody[1D3] and PE Anti-Mouse CD40 Antibody[FGK4.5/FGK45] (left) or PE Rat IgG2a, κ Isotype Control (right). Total viable cells were used for analysis.

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