PE Anti-Mouse CD49b/pan-NK cells Antibody[DX5]

货号：GFH1116D

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100 Tests 50 Tests 100 Tests × 2

Alternate Names	CD49 antigen-like family member B, CD49b, Collagen receptor, GPIa, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha, pan-NK cells
Cellular Localization	Membrane
Clone No	DX5
Isotype	Rat IgM, κ
Leadtime	咨询
Background	DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Abbre	CD49b
Swissprot	Q62469
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	PE Rat IgM, κ Isotype Control[RTK2118]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE
Conjugation Information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	16398

C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD161/NK1.1 Antibody and PE Anti-Mouse CD49b Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD161/NK1.1 Antibody and PE Rat IgM, κ Isotype Control (Right).

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