PE/Cyanine5.5 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]

货号：GFH1131I

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100 Tests 50 Tests 100 Tests × 2

Alternate Names	Programmed Death-1, PD-1
Cellular Localization	Membrane
Clone No	29F.1A12
Isotype	Rat IgG2a, κ
Leadtime	咨询
Background	CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
Abbre	CD279
Swissprot	Q02242
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	PE/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE/Cyanine 5.5
Conjugation Information	PE/Cyanine5.5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 690 nm (e.g., a 690/50 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	18566

Con-A stimulated C57BL/6 splenocytes (3 days) are stained with PE/Cyanine5.5 Anti-Mouse CD279/PD-1 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

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