PE/Cyanine5 Anti-Mouse CD122/IL-2RB Antibody[5H4]

货号：GFH1029G

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Alternate Names	IL-2R subunit beta, CD122, High affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2RB, Il2rb, Interleukin-2 receptor subunit beta, p70-75
Cellular Localization	Membrane
Clone No	5H4
Isotype	Rat IgG2a, κ
Leadtime	咨询
Background	CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Abbre	CD122
Swissprot	P16297
Host	Rat
Reactivity	Mouse
Clonality	Monoclonal
Isotype Control	PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE/Cyanine 5
Conjugation Information	PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	16185

C57BL/6 murine splenocytes are stained with PE/Cyanine5 Anti-Mouse CD122 Antibody and Elab Fluor^® 488 Anti-Mouse CD3 Antibody (Left). Splenocytes stained with Elab Fluor^® 488 Anti-Mouse CD3 Antibody (Right) are used as control.

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