PE/Cyanine7 Anti-Human CD158b/j Antibody[DX27]

货号：GFH1381H

Price: ¥3120.00 ¥1320.00 ¥5100.00

Size:

100 Tests 20 Tests 100 Tests × 2

Cellular Localization	Membrane
Clone No	DX27
Isotype	Mouse IgG2a, κ
Leadtime	咨询
Background	CD158b is expressed on natural killer cells and a subset of T cells. It is a member of the immunoglobulin superfamily containing two immunoglobulin C2-type domains. Both variants and alternative isoforms of CD158b have been reported. The interaction of CD158b with specific HLA-C antigens on a target cell (HLA-Cw1, HLA-Cw3, HLA-Cw7 alleles, for example) inhibits cytotoxicity and prevents target cell lysis and death. The interactions between KIR and MHC class I are thought to be important in NK cell and T cell regulation following antigen stimulation. The absence of ligands for KIRs may lower the threshold for activation through activating receptors and increase inflammation and susceptibility to autoimmune disease.
Abbre	CD158b/j
Swissprot	P43627, P43628
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	PE/Cyanine7 Mouse IgG2a, κ Isotype Control[C1.18.4]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PE/Cyanine 7
Conjugation Information	PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date	12个月
Shipping	冰袋
Gene ID	3803

Staining of normal human peripheral blood cells with FITC Anti-Human CD16 Antibody and PE/Cyanine7 Anti-Human CD158b/j Antibody[DX27] (left) or PE/Cyanine7 Mouse IgG2a, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.

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