PE/Elab Fluor® 594 Anti-Human CD49d Antibody[9F10]

  • 货号:GFH1144P
PE/Elab Fluor® 594 Anti-Human CD49d Antibody[9F10]
  • PE/Elab Fluor® 594 Anti-Human CD49d Antibody[9F10]

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Size:
100 Tests 20 Tests 100 Tests × 2
Alternate Names
CD49 antigen-like family member D, CD49d, ITGA4, Integrin alpha-4, Integrin alpha-IV, VLA-4 subunit alpha
Cellular Localization
Membrane
Clone No
Isotype
Mouse IgG1, κ
Leadtime
咨询
Background
CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.
Abbre
CD49d
Swissprot
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype Control
PE/Elab Fluor® 594 Mouse IgG1, κ Isotype Control[MOPC-21]
Applications
FCM
Form
Liquid
Concentration
5 μL/Test
Conjugation
PE/Elab Fluor®594
Conjugation Information
PE/Elab Fluor® 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date
12个月
Shipping
冰袋
Gene ID
Human peripheral blood lymphocytes are stained with PE/Elab Fluor® 594 Anti-Human CD49d Antibody[9F10] (filled gray histogram) or PE/Elab Fluor® 594 Mouse IgG1, κ Isotype Control (empty black histogram).
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