PerCP/Cyanine5.5 Anti-Human CD194/CCR4 Antibody[L291H4]

货号：GFH1366J

Price: ¥3600.00 ¥1332.00 ¥7776.00

Size:

100 Tests 20 Tests 100 Tests × 2

Alternate Names	CC-CKR-4, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, MGC88293
Cellular Localization	Membrane
Clone No	L291H4
Isotype	Mouse IgG1, κ
Leadtime	咨询
Background	CD194, also known as CCR4, is a CC chemokine receptor. It binds CCL17 and CCL22 and is expressed on a subset of T and B cells, basophils, monocytes, and NK cells. Human Th2 cells are characterized by the expression of CCR4 and CCR8, and these receptors are regulated differently during Th2 development. Human peripheral blood Tregs can be divided into two distinct populations based on the expression of CCR4. Freshly isolated Tregs express CCR4 and presumably represent memory-type Tregs, and CCR4- Tregs require CD3-mediated activation to acquire a regulatory activity. Depletion of CCR4+ T cells leads to Th1-type polarization of CD4+ T cells and augmentation of CD8+ T cell responses to tumor antigens. CCR4 and its ligands are important for the recruitment of memory T cells into the skin in various cutaneous immune diseases.
Abbre	CD194
Swissprot	P51679
Host	Mouse
Reactivity	Human
Clonality	Monoclonal
Isotype Control	PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Applications	FCM
Form	Liquid
Concentration	5 μL/Test
Conjugation	PerCP/Cyanine 5.5
Conjugation Information	PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage	This product can be stored at 2-8°C for 12 months. Do not freeze.
Expiration Date	12个月
Shipping	冰袋

Human peripheral blood lymphocytes are stained with FITC Anti-Human CD3 Antibody and PerCP/Cyanine5.5 Anti-Human CD194/CCR4 Antibody[L291H4] (Left). Lymphocytes are stained with FITC Anti-Human CD3 Antibody and PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control (Right).

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