Purified Anti-Human CD152 Antibody[BNI3]

GRD, ALPS, IDDM, Cytotoxic T-lymphocyte protein, Cytotoxic T-lymphocyte-associated antigen, Cytotoxic T-Lymphocyte-Associated Protein, CELIAC, CTLA4, ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, Cytotoxic T-Lymphocyte-Associated Protein 4

BNI3

Mouse IgG2a, κ

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FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

CD152

Mouse

Human

Monoclonal

>98%, Protein A/G purified

FCM

≥ 1 mg/mL

Unconjugated

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

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